diff -Nru drop-seq-2.5.1+dfsg/debian/changelog drop-seq-2.5.1+dfsg/debian/changelog
--- drop-seq-2.5.1+dfsg/debian/changelog	2022-01-16 15:45:58.000000000 +0000
+++ drop-seq-2.5.1+dfsg/debian/changelog	2022-02-22 20:15:50.000000000 +0000
@@ -1,3 +1,10 @@
+drop-seq (2.5.1+dfsg-2) unstable; urgency=medium
+
+  * Team upload
+  * Depending on libbiojava5-java instead of libbiojava4-java
+
+ -- Pierre Gruet <pgt@debian.org>  Tue, 22 Feb 2022 21:15:50 +0100
+
 drop-seq (2.5.1+dfsg-1) unstable; urgency=medium
 
   * New upstream version
diff -Nru drop-seq-2.5.1+dfsg/debian/control drop-seq-2.5.1+dfsg/debian/control
--- drop-seq-2.5.1+dfsg/debian/control	2022-01-16 15:45:58.000000000 +0000
+++ drop-seq-2.5.1+dfsg/debian/control	2022-02-22 19:43:06.000000000 +0000
@@ -6,7 +6,7 @@
 Build-Depends: debhelper-compat (= 13),
                javahelper,
                default-jdk-headless,
-               libbiojava4.0-java,
+               libbiojava5-java,
                libhtsjdk-java,
                libpicard-java,
                libcommons-collections4-java,
@@ -31,7 +31,7 @@
          default-jre | java-runtime,
          java-wrappers,
          picard-tools,
-         libbiojava4.0-java,
+         libbiojava5-java,
          libpicard-java,
          libcommons-collections4-java,
          libcommons-lang-java,
diff -Nru drop-seq-2.5.1+dfsg/debian/drop-seq-tools.manifest drop-seq-2.5.1+dfsg/debian/drop-seq-tools.manifest
--- drop-seq-2.5.1+dfsg/debian/drop-seq-tools.manifest	2022-01-16 15:45:58.000000000 +0000
+++ drop-seq-2.5.1+dfsg/debian/drop-seq-tools.manifest	2022-02-22 19:43:31.000000000 +0000
@@ -1,3 +1,3 @@
 usr/share/java/dropseq.jar:
  Main-Class: org.broadinstitute.dropseqrna.cmdline.DropSeqMain
- Class-Path: /usr/share/java/guava.jar /usr/share/java/gson.jar /usr/share/java/htsjdk.jar /usr/share/java/picard.jar /usr/share/java/commons-collections4.jar /usr/share/java/commons-io.jar /usr/share/java/commons-lang.jar /usr/share/java/commons-math3.jar /usr/share/java/barclay.jar /usr/share/java/la4j.jar /usr/share/java/snakeyaml.jar /usr/share/java/biojava4-alignment.jar /usr/share/java/biojava4-core.jar
+ Class-Path: /usr/share/java/guava.jar /usr/share/java/gson.jar /usr/share/java/htsjdk.jar /usr/share/java/picard.jar /usr/share/java/commons-collections4.jar /usr/share/java/commons-io.jar /usr/share/java/commons-lang.jar /usr/share/java/commons-math3.jar /usr/share/java/barclay.jar /usr/share/java/la4j.jar /usr/share/java/snakeyaml.jar /usr/share/java/biojava5-alignment.jar /usr/share/java/biojava5-core.jar
diff -Nru drop-seq-2.5.1+dfsg/debian/rules drop-seq-2.5.1+dfsg/debian/rules
--- drop-seq-2.5.1+dfsg/debian/rules	2022-01-16 15:45:58.000000000 +0000
+++ drop-seq-2.5.1+dfsg/debian/rules	2022-02-22 19:43:52.000000000 +0000
@@ -17,8 +17,8 @@
 	dh_auto_configure
 	mkdir -p lib/test
 	ln -s /usr/share/java/commons-collections4.jar lib/commons-collections4.jar
-	ln -s /usr/share/java/biojava4-alignment.jar lib/biojava4-alignment.jar
-	ln -s /usr/share/java/biojava4-core.jar lib/biojava4-core.jar
+	ln -s /usr/share/java/biojava5-alignment.jar lib/biojava5-alignment.jar
+	ln -s /usr/share/java/biojava5-core.jar lib/biojava5-core.jar
 	ln -s /usr/share/java/commons-io.jar lib/commons-io.jar
 	ln -s /usr/share/java/commons-lang.jar lib/commons-lang.jar
 	ln -s /usr/share/java/commons-math3.jar lib/commons-math3.jar