software tool to compute gene structure predictions

 GenomeThreader is a software tool to compute gene structure predictions.
 The gene structure predictions are calculated using a similarity-based
 approach where additional cDNA/EST and/or protein sequences are used to
 predict gene structures via spliced alignments. GenomeThreader was motivated
 by disabling limitations in GeneSeqer, a popular gene prediction program
 which is widely used for plant genome annotation.