approximate comparative metagenomics method dedicated to NGS datasets

 Simka is a de novo comparative metagenomics tool. Simka represents each
 dataset as a k-mer spectrum and compute several classical ecological
 distances between them.
 .
 The difference with Simka stands in the fact that SimkaMin outputs
 approximate (but very similar) results by subsampling the kmer space.
 With this strategy, and with default parameters, SimkaMin is an order
 of magnitude faster, uses 10 times less memory and 70 times less disk
 than Simka.